Review article

Oral Lichen Ruber - II Immunoreaction

Dolores Biočina-Lukenda

Abstract

Immunological disorder in oral lichen ruber (OLR) is related to cell mediated immunological reaction which can imply various immunological disorders in the oral mucous membrane. Changed immunoreaction characterized by suppressed function of phagocyte and NK-cells reduce the possibility of elimination of the bacterial antigens with possible resultant onset of autoimmune disorders, stressing the importance of nonspecific immunity. Evaluation of cell mediated immunity is based on phenotypic and functional analysis of peripheral blood cells by monoclonal antibodies. T-cell mediated suppression has an important role in maintaining its own tolerance, so the disorder of T-cells is included in the pathogenesis of autoimmune diseases. A consequence of this could be activation of immature T-lymphocytes, causing cellular autoreactivity in OLR. Disorder of cell mediated immunity could reflect on the humoral immunity condition. Humoral immunity in patients with OLR has been reported, but with inconsistent results. The result of humoral immunity is not specific, but is a consequence of the changed immunoreaction of patients with OLR caused by other immunological disorders and diseases where oral lichen could manifest

Keywords

oral lichen ruber; immunoreaction; nonspecific and specific immunity

Hrčak ID:

10359

URI

https://hrcak.srce.hr/10359

Publication date:

15.12.2002.

Article data in other languages: croatian

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