Professional paper
https://doi.org/10.15644/asc47/3/5
Aquacel® Ag and Ozone in Bisphosphonate Induced Osteonecrosis of the Jaws (BIONJ) Therapy: a Case Report
Ivan Brakus
; Department of Oral Surgery, Study of Medicine University of Split
Ratka BORIĆ BRAKUS
; Department of prosthodontics, Study of Medicine University of Split
Kolja Poljak
; Department of Otorhinolaryngology, Clinical Hospital Split
Irina FILIPOVIĆ ZORE
; Department of Oral Surgery, School of Dental Medicine University of Zagreb
Abstract
Objective: Bisphosphonate induced osteonecrosis of the jaw (BIONJ) is often seen in oncologic patients with bone metastasis, who are treated with intravenous bisphosphonates as a result of elective dental treatment. Clinical course: We present a case report of a 68-year-old patient with BIONJ in the right maxillary premolar region after a tooth extraction. The patient had breast cancer, bone metastasis, and received intravenous bisphosphonate therapy and anti-mitotic chemotherapy. Conservative therapy for stages 1 and 2 of BIONJ was indicated with mouth washes, antibiotics and, in addition, local Aquacel Ag wound dressing and HealOzone therapy. After 6 months of drug absence (bisphosphonates), the surgical procedure was performed and the patient obtained a removable prosthetic appliance. Discussion and conclusion: Conservative treatment in addition with Aquacel Ag and HealOzone reduced pain and infection in the waiting period, but the wound did not heal. The surgical procedure after the drug treatment was an efficient solution. Prevention is the best treatment of BIONJ.
Keywords
Biphosphonates; Carboxymethylcellulose Sodium; Ozone; Osteonecrosis; Jaw; Pamidronate
Hrčak ID:
108219
URI
Publication date:
15.9.2013.
Visits: 2.400 *