Editorial

HRVATSKI KONSENZUS O LIJEČENJU UPALNIH BOLESTI CRIJEVA BIOLOŠKOM TERAPIJOM

BORIS VUCELIĆ ; Referral Center of the Ministry of Health of the Republic of Croatia for Chronic Inflammatory Bowel Diseases, IBD Section, Croatian Society of Gastroenterology, Zagreb, Croatia
SILVIJA ČUKOVIĆ-ČAVKA ; Referral Center of the Ministry of Health of the Republic of Croatia for Chronic Inflammatory Bowel Diseases, IBD Section, Croatian Society of Gastroenterology, Zagreb, Croatia
MARKO BANIĆ ; Referral Center of the Ministry of Health of the Republic of Croatia for Chronic Inflammatory Bowel Diseases, IBD Section, Croatian Society of Gastroenterology, Zagreb, Croatia
ANTE BILIĆ ; Referral Center of the Ministry of Health of the Republic of Croatia for Chronic Inflammatory Bowel Diseases, IBD Section, Croatian Society of Gastroenterology, Zagreb, Croatia
VLADIMIR BORZAN ; Referral Center of the Ministry of Health of the Republic of Croatia for Chronic Inflammatory Bowel Diseases, IBD Section, Croatian Society of Gastroenterology, Zagreb, Croatia
MARKO DUVNJAK ; Referral Center of the Ministry of Health of the Republic of Croatia for Chronic Inflammatory Bowel Diseases, IBD Section, Croatian Society of Gastroenterology, Zagreb, Croatia
MIROSLAVA KATIČIĆ ; Referral Center of the Ministry of Health of the Republic of Croatia for Chronic Inflammatory Bowel Diseases, IBD Section, Croatian Society of Gastroenterology, Zagreb, Croatia
SANJA KOLAČEK ; Referral Center of the Ministry of Health of the Republic of Croatia for Chronic Inflammatory Bowel Diseases, IBD Section, Croatian Society of Gastroenterology, Zagreb, Croatia
ŽELJKO KRZNARIĆ ; Referral Center of the Ministry of Health of the Republic of Croatia for Chronic Inflammatory Bowel Diseases, IBD Section, Croatian Society of Gastroenterology, Zagreb, Croatia
MILAN KUJUNDŽIĆ ; Referral Center of the Ministry of Health of the Republic of Croatia for Chronic Inflammatory Bowel Diseases, IBD Section, Croatian Society of Gastroenterology, Zagreb, Croatia
MARINKO MARUŠIĆ ; Referral Center of the Ministry of Health of the Republic of Croatia for Chronic Inflammatory Bowel Diseases, IBD Section, Croatian Society of Gastroenterology, Zagreb, Croatia
SILVIO MIHALJEVIĆ ; Referral Center of the Ministry of Health of the Republic of Croatia for Chronic Inflammatory Bowel Diseases, IBD Section, Croatian Society of Gastroenterology, Zagreb, Croatia
BRANKICA SINČIĆ MIJANDRUŠIĆ ; Referral Center of the Ministry of Health of the Republic of Croatia for Chronic Inflammatory Bowel Diseases, IBD Section, Croatian Society of Gastroenterology, Zagreb, Croatia
MLADEN PERŠIĆ ; Referral Center of the Ministry of Health of the Republic of Croatia for Chronic Inflammatory Bowel Diseases, IBD Section, Croatian Society of Gastroenterology, Zagreb, Croatia
MIROSLAV ŠIMUNIĆ ; Referral Center of the Ministry of Health of the Republic of Croatia for Chronic Inflammatory Bowel Diseases, IBD Section, Croatian Society of Gastroenterology, Zagreb, Croatia
BRUNO ŠKURLA ; Referral Center of the Ministry of Health of the Republic of Croatia for Chronic Inflammatory Bowel Diseases, IBD Section, Croatian Society of Gastroenterology, Zagreb, Croatia

Abstract

Uvođenje biološke terapije u kliničku praksu je značajan napredak u liječenju kroničnih upalnih bolesti crijeva, prije svega zbog
njihove dokazane djelotvornosti te činjenice da su to prvi lijekovi kojima se uspjelo promijeniti prirodni tijek tih bolesti. Radi se,
međutim, o vrlo skupim lijekovima s vrlo kompleksnim mehanizmima djelovanja i mogućim nuspojavama, te njihovo korištenje u
vrlo kompliciranim bolestima kakve su upalne bolesti crijeva zahtijeva smjernice bazirane na rezultatima dobro kontroliranih studija.
Referentni centar Ministarstva zdravlja i Sekcija za upalne bolesti crijeva Hrvatskog gastroenterološkog društva organizirali
su stoga konsenzus konferenciju tijekom koje su definirane hrvatske smjernice za liječenje upalnih bolesti crijeva anti-TNF lijekovima.
Tekst sa smjernicama uključuje definicije upalnih bolesti crijeva, opće principe liječenja upalnih bolesti crijeva, važnost
mukoznog cijeljenja, analizu razloga nedjelotvornosti i gubitka djelotvornosti anti-TNF terapije, daje preporuke o dužini terapije,
daje smjernice za probir na oportunističke infekcije prije početka anti-TNF terapije, osvrće se na probleme reprodukcije vezane
za anti-TNF terapiju te konačno daje smjernice za liječenje raznih fenotipova upalnih bolesti crijeva i ekstraintestinalnih manifestacija
upalnih bolesti crijeva.

Keywords

upalne bolesti crijeva; ulcerozni kolitis; Crohnova bolest; biološka terapija; hrvatski konsenzus

Hrčak ID:

111250

URI

https://hrcak.srce.hr/111250

Publication date:

28.11.2013.

Article data in other languages: english

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