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HEPATITIS C: WHO SHOULD BE TREATED?

DAVOR ŠTIMAC ; Rijeka University Hospital Center, Clinical Department of Medicine, Department of Gastroenterology, Rijeka, Croatia
NIKOLA BRADARIĆ ; Split University Hospital Center, Clinical Department of Infectious Diseases, Split, Croatia
SANDRA MILIĆ ; Rijeka University Hospital Center, Clinical Department of Medicine, Department of Gastroenterology, Rijeka, Croatia

Abstract

Therapy is strongly recommended in patients with acute infection, patients with elevated ALT levels, patients with normal ALT level and F ≥2 METAVIR score, in genotype 1 nonresponders and relapsers to antiviral therapy with triple therapy (pegylated interferon, ribavirin, bocaprevir or telaprevir), in patients with compensated cirrhosis and patients on hemodialysis. It is possible to treat patients with HBV and HIV co-infection, patients with severe HCV extrahepatic manifestations and patients with transplanted liver. Drug users and alcoholics can be treated after 6-month abstinence, but also with supportive therapy. This therapy is not recommended in patients with fulminant hepatitis, patients with persistent normal ALT levels and without fibrosis, in kidney transplant recipients and in pregnant women.

Keywords

hepatitis C; treatment; patient selection

Hrčak ID:

113719

URI

https://hrcak.srce.hr/113719

Publication date:

14.1.2014.

Article data in other languages: croatian

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