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Croatian Medical Journal, Vol. 54 No. 5, 2013.

Original scientific paper

https://doi.org/10.3325/cmj.2013.54.436

The relationship between depressive syndrome and suicidal risk in patients with acute schizophrenia

Dario Bagarić ; Department for Integral Psychiatry Psychiatric University Hospital Vrapče, Zagreb, Croatia
Petrana Brečić ; Department for Treatment and Rehabilitation, Psychiatric University Hospital Vrapče, Zagreb, Croatia
Draženka Ostojić ; Department for Diagnostics and Intensive Care, PsychiatricUniversity Hospital Vrapče, Zagreb, Croatia
Vlado Jukić ; Department for Forensic Psychiatry, Psychiatric University Hospital Vrapče, Zagreb, Croatia
Ana Goleš ; Psychiatric University Hospital Vrapče, Zagreb, Croatia

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Abstract

Aim To determine the relationship between scores on
five factors of the Positive and Negative Syndrome Scale
(PANSS) and Calgary Depression scale for Schizophrenia
(CDSS) and scores on the InterSePT Scale for Suicidal Thinking
(ISST) in patients with acute schizophrenia.
Methods Data were collected on sociodemographic
and clinical characteristics of 180 drug-treated in-patients
with acute schizophrenia. Their symptoms were assessed
with PANSS, CDSS, and ISST and correlations between the
scores were calculated. Statistically significant correlations
were included in the logistic regression analysis to identify
predictors of suicidal risk.
Results CDSS (P < 0.001) score and negative (P < 0.001),
disorganized (P = 0.041), emotional (P < 0.001), and total
score on PANSS (P < 0.001) showed a significant positive
correlation with ISST. Stepwise logistic regression analysis
revealed that CDSS scores (odds ratio [OR] 5.18; confidence
interval [CI] 1.58-16.95), and disorganized (0.90; 0.81-0.99)
and emotional (1.15; 1.01-1.30) factors of PANSS were predictors
of suicidal risk.
Conclusion Our results suggested a considerable association
between depressive syndrome as assessed by the
PANSS emotional factor and CDSS score and suicidal risk in
patients with acute schizophrenia.

Keywords

Hrčak ID:

117008

URI

https://hrcak.srce.hr/117008

Publication date:

15.10.2013.

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