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Croatian Medical Journal, Vol. 54 No. 6, 2013.

Original scientific paper

https://doi.org/10.3325/cmj.2013.54.555

Carotid atherosclerosis and right ventricular diastolic dysfunction in a sample of hypertensive Nigerian patients

Adeseye A. Akintunde ; Department of Medicine, LAUTECH Teaching Hospital, Ogbomoso, Nigeria
Philip B. Adebayo ; Department of Medicine, LAUTECH Teaching Hospital, Ogbomoso, Nigeria
Ademola A. Aremu ; Department of Radiology, LAUTECH Teaching Hospital Ogbomoso, Nigeria
Oladimeji G. Opadijo ; Department of Medicine, LAUTECH Teaching Hospital, Ogbomoso, Nigeria

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Abstract

Aim To determine the association of carotid atherosclerosis
and right ventricular diastolic dysfunction (DD) among
treated hypertensive Nigerian patients.
Methods This was a single center cross-sectional study
performed at the Cardiology Clinic of LAUTECH Teaching
Hospital, Ogbomoso, Nigeria between January and December
2012. The study included 122 hypertensive Nigerians
(mean age, 57.3 ± 14.7 years, 36.9% women). Patients’
clinical, demographic, and echocardiographic parameters
were obtained. Diastolic dysfunction was assessed with
the trans-tricuspid Doppler flow.
Results Patients with DD were significantly older than
those with normal diastolic function. Mean and maximum
carotid intima media thickness measurements were significantly
higher among patients with right ventricular DD
than in those with normal diastolic function. Mean systolic
blood pressure (148.3 ± 31.9 vs 128.0 ± 2.8 mm Hg,
P = 0.049) and interventricular septal thickness in diastole
(12.8 ± 2.3 vs 11.6 ± 2.8 mm, P = 0.048) were significantly
higher and tricuspid annular pulmonary systolic excursion
(33.6 ± 4.9 vs 23.0 ± 4.2 mm, P = 0.035) was significantly lower
in patients with right ventricular DD than in those with
normal diastolic function. Carotid intima media thickness
measurements were correlated with early trans-tricuspid
Doppler flow and early transtricuspid diastolic flow/late
right atrial transtricupsid diastolic flow ratio.
Conclusion Right ventricular DD in hypertensive patients
was significantly correlated with increased carotid atherosclerosis.
Carotid intima media thickness measurements
may therefore be a surrogate marker for DD in hypertensive
subjects.

Keywords

Hrčak ID:

117023

URI

https://hrcak.srce.hr/117023

Publication date:

15.12.2013.

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