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Sarcomatoid carcinoma of the pleura – a case report

Mile Bogdan ; Klinika za plućne bolesti „Jordanovac“, KBC Zagreb, Zagreb
Dražena Srdić ; Klinika za plućne bolesti „Jordanovac“, KBC Zagreb, Zagreb
Sanja Pleština ; Klinika za plućne bolesti „Jordanovac“, KBC Zagreb, Zagreb
Luka Brčić ; Zavod za patologiju, Medicinski fakultet Sveučilišta u Zagrebu, Zagreb

Abstract

Abstract. Aim: To report the case of a 57-year-old patient, who came with suspicion of pleural mesothelioma, and to emphasise the importance of histological analysis of tumour. Case report: Chest CT scan revealed numerous solid well-vascularized tumour formations of the left pleura with large pleural effusion. Fiber-broncho-cytological processing revealed no malignant cells, whereas the cytological analysis of pleural punctate corresponded to the lymphocytic type of effusion with no malignant cells. Histopathological analysis confirmed poorly differentiated sarcomatoid carcinoma. The patient was treated with cytostatic chemotherapy according to MAID protocol (Mesna, doxorubicin, ifosfamide, and dacarbazine). After four chemotherapy cycles, pleural effusion partially regressed. Conclusion: Sarcomatoid carcinoma of the pleura is a very rare tumour of thorax. It represents a differential diagnostic problem because it can imitate other diseases, especially mesothelioma. In the presented case, the diagnosis was made using histopathological and immunohistochemical analysis of tumour. The choice of treatment is systematic cytostatic chemotherapy, and the prognosis is much better with lung cancer

Keywords

pleura; pleural neoplasms; sarcomatoid carcinoma

Hrčak ID:

118583

URI

https://hrcak.srce.hr/118583

Publication date:

3.3.2014.

Article data in other languages: croatian

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