Paediatria Croatica, Vol. 58 No. 1, 2014.
Professional paper
https://doi.org/10.13112/PC.2014.13
Perinatal management of a newborn with neural tube defect: case report
Zora Zakanj
; KBC Sestre milosrdnice
Igor Šegović
; ŽB Čakovec
Venera Zahariev
; DZ zagrebačke županije
Abstract
Neural tube defects are the most common congenital anomalies of the central nervous system. Myelomeningocele is the most often
and severe form. It results from failure of the neural tube to close spontaneously between the 3rd and 4th week of intrauterine development.
The precise cause remains unknown; evidence suggests many factors such as hyperthermia, drugs, malnutrition, maternal
obesity, diabetes, and folic acid defi ciency. It typically presents as a saclike cystic structure covered by a thin layer of partially epithelialized
tissue. Maternal periconceptual folic acid supplementation can reduce the incidence of neural tube defects. We present
perinatal care of a newborn with lumbosacral myelomeningocele associated with hydrocephalus and Chiari II malformation.
Keywords
neural tube defects; meningomyelocele; congenital abnormalities; central nervous system; infant, newborn
Hrčak ID:
120008
URI
Publication date:
24.3.2014.
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