Original scientific paper

Severe Acute Pancreatitis as a Part of Multiple Dysfunction Syndrome

Vladimir Gašparović ; University of Zagreb, School of Medicine, University Hospital Centre Zagreb, Intensive Care Unit, Department of Medicine, Zagreb, Croatia
Kristina Đaković ; University of Zagreb, School of Medicine, University Hospital Centre Zagreb, Intensive Care Unit, Department of Medicine, Zagreb, Croatia
Ivan Gornik ; University of Zagreb, School of Medicine, University Hospital Centre Zagreb, Intensive Care Unit, Department of Medicine, Zagreb, Croatia
Radovan Radonić ; University of Zagreb, School of Medicine, University Hospital Centre Zagreb, Intensive Care Unit, Department of Medicine, Zagreb, Croatia

Abstract

Acute pancreatitis is a disease with various degrees of clinical manifestations. Mild and moderate severe acute pancreatitis is an illness characterized with chemical inflammation which, in general, passes without major complications. Clinical picture of severe acute pancreatitis other side is commonly complicated with functional deterioration of other organs, and frequently has characteristics of multiple organ dysfunction or failure syndrome with or without bacterial super infection. We studied 82 patients admitted to the intensive care unit with severe acute pancreatitis, 14 died. The mortality was in statistically significant correlation with the severity of clinical condition at admission assessed by APACHE II score, and higher Ranson’s and Glasgow criteria by admission. Adequate volume supplementation, on time, as well as percutaneous drainage of infected pancreas collection reduces a risk of pure outcome.

Keywords

acute pancreatitis; bacterial super infection; multiple organ failure

Hrčak ID:

120805

URI

https://hrcak.srce.hr/120805

Publication date:

31.3.2014.

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