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Collegium antropologicum, Vol. 38 No. 1, 2014.

Original scientific paper

Evaluation of Sentinel Node Biopsy in Oral Carcinomas

Aleksandar Milenović ; University of Zagreb, University Hospital Dubrava, Clinic for Oral and Maxillofacial Surgery, Zagreb, Croatia
Mišo Virag ; University of Zagreb, University Hospital Dubrava, Clinic for Oral and Maxillofacial Surgery, Zagreb, Croatia
Predrag Knežević ; University of Zagreb, University Hospital Dubrava, Clinic for Oral and Maxillofacial Surgery, Zagreb, Croatia
Vanja Vučićević Boras ; University of Zagreb, University Hospital Center Zagreb, Zagreb, Croatia
Karmen Trutin Ostović ; University of Zagreb, University Hospital Dubrava, MIAC Centre of Clinical Cytology and Cytometry, Zagreb, Croatia
Dragana Gabrić Pandurić ; University of Zagreb, School of Dental Medicine, Department of Oral Surgery, Zagreb, Croatia
Mato Sušić ; University of Zagreb, School of Dental Medicine, Department of Oral Surgery, Zagreb, Croatia

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Abstract

It is still a matter of debate whether sentinel node biopsy might replace neck dissection in patients with clinically negative neck lymph nodes who suffer from oral squamous cell carcinoma. In 30 patients (26 male, 4 female, average age 59.4 years) with oral squamous cell carcinoma we performed ultrasound guided punction of the lymph nodes which were lymphoscintigraphically seen together with histopatological analysis of the dissected node. Sentinel lymph node was seen in 93% cases. By use of lymphoscintigraphy sentinel node was verified in 23 patients. Ultrasound guided punction showed presence of regional disease in 10% of cases, whereas sentinel biopsy revealed 23 of the converted necks. Histopathological findings were positive in 33% of our patients. The results of this study revealed that sentinel biopsy did not reveal 27% of the patients with positive neck histopathology. In conclusion, sentinel node biopsy should be performed in selective cases as in some localizations it is easier to perform neck dissection in comparison to the sentinel node biopsy.

Keywords

oral squamous cell carcinoma; sentinel node biopsy; histopathology; lymphoscintigraphy

Hrčak ID:

120913

URI

https://hrcak.srce.hr/120913

Publication date:

31.3.2014.

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