Review article

Inflammatory bowel disease

Boris Vucelić ; Department for Gastroenterology and Hepatology, Clinic for Internal Medicine, Clinical Hospital Centre Zagreb, Zagreb, Croatia

Abstract

Inflammatory bowel disease (IBD) is heterogenous group of inflammatory disorders characterized by chronic immune activation and inflammation of the gastrointestinal tract, associated with numerous extraintestinal manifestations.
Two most important forms are Crohn’s disease and ulcerative colitis with several phenotypes. Etiopathogenesis of IBD is still unknown.
Diagnostic and therapeutic approach of IBD is very complex and requires excellent knowledge of the clinical course and complications of the disease itself and therapy.
The paper provides present therapeutic strategy with emphasis on the importance of mucosal healing and analysis of present knowledge of the role of biologics in the therapy of IBD.

Keywords

inflammatory bowel disease; ulcerative colitis; Crohn’s disease

Hrčak ID:

123330

URI

https://hrcak.srce.hr/123330

Publication date:

17.10.2013.

Article data in other languages: croatian

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