Reumatizam, Vol. 60 No. 2, 2013.
Professional paper
Classification of vasculitides
Branimir Anić
; Department for Clinical Immunology and Rheumatology, Clinic for Internal Medicine, Clinical Hospital Centre Zagreb, Zagreb, Croatia
Mislav Cerovec
; Department for Clinical Immunology and Rheumatology, Clinic for Internal Medicine, Clinical Hospital Centre Zagreb, Zagreb, Croatia
Abstract
Vasculitides are heterogeneous group of inflammatory diseases with one common feature - inflammation in the blood vessel wall. The diagnosis of vasculitides is probably one of the biggest challenges in medicine. Clinical presentation of the disease depends on the extent of affection of single organ or organ systems and the total number of affected organs. A broad spectrum of clinical manifestations and low incidence of the disease makes it difficult to conduct a systematic clinical research of the disease. Everyday practise and a need for systemic clinical research of the disease necessitate the differentiation of individual entities that constitute this heterogeneous group of the inflammatory diseases. In past decades various concepts of the disease classification were proposed - according to the etiology, pathogensis, type of immune response in the blood vessel wall, histological findings in the affected vessels or depending on the involment of particular organs and organ systems. None of the proposed methods of the classification of vasculitides was entirely adequate. This paper briefly presents the historical development of the classification of the vasculitides. The emphasis of this paper was on the novelties from the recent classification and nomenclature of vasculitides that was proposed at the second consensus conference held in Chapel Hill.
Keywords
Hrčak ID:
123332
URI
Publication date:
17.10.2013.
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