Professional paper

Laboratory diagnostics of polymyositis/dermatomyositis

Višnja Prus ; Clinical Department for Rheumatology, Allergology and Clinical Immunology, Clinic for Internal Medicine, Clinical Hospital Centre Osijek, Osijek, Croatia
Dražen Bedeković ; Clinical Department for Rheumatology, Allergology and Clinical Immunology, Clinic for Internal Medicine, Clinical Hospital Centre Osijek, Osijek, Croatia

Abstract

Polymyositis/dermatomyositis is chronic systemic inflammatory disease that usually affects the skin and muscle tissue. The diagnosis of polymyositis/dermatomyositis isn’t simple, and represents challenge for clinicians, it is based on the integration of results: medical history and clinical presentation, laboratory findings enzymes more or less specific to muscle tissue, myositis-specific autoantibodies and autoantibodies associated with myositis which can be found at other inflammatory connective tissue diseases without myositis, electromyography findings, and biopsy of muscle and skin. Laboratory tests contribute and assist in the diagnosis of polymyositis/dermatomyositis but they should always be evaluated in context with clinical picture and other tests and decisions about diagnosis and/or treatment are based on the integration of the results.

Keywords

polymyositis; dermatomyositis; laboratory tests; autoantibodies

Hrčak ID:

124036

URI

https://hrcak.srce.hr/124036

Publication date:

25.10.2012.

Article data in other languages: croatian

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