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Reumatizam, Vol. 57 No. 2, 2010.

Conference paper

Scleroderma renal crisis

Jadranka Morović-Vergles ; Department for Clinical Immunology and Rheumatology, Clinic for Internal Medicine, Clinical Hospital “Dubrava”, Zagreb, Croatia
Melanie-Ivana Čulo ; Department for Clinical Immunology and Rheumatology, Clinic for Internal Medicine, Clinical Hospital “Dubrava”, Zagreb, Croatia
Dušanka Martinović Kaliterna ; Department for Clinical Immunology and Rheumatology, Clinic for Internal Medicine, Clinical Hospital Centre Split, Split, Croatia

Full text: croatian pdf 430 Kb

page 109-111

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Abstract

Systemic sclerosis (SSc) is a multisystem disease whose clinical manifestations result from inflammation, vascular injury and obliteration, and cutaneous and visceral fibrosis. Scleroderma renal crisis (SRC) occurs in 5% of patients with particullary diffuse form of SSc. It is characterized by malignant hypertension and oligo/anuric acute renal failure. SRC was once a uniformly fatal complication of SSc. The prognosis of SRC has significantly improved with the introduction of angiotensin-converting enzyme inhibitors (ACEi) as treatment. The treatment of SRC relies on tight control of blood pressure and aggressive treatment with ACEi, if needed in combination with other types of antihypertensive drugs.

Keywords

systemic sclerosis; renal lesion; scleroderma renal crisis (SRC); treatment

Hrčak ID:

124634

URI

https://hrcak.srce.hr/124634

Publication date:

14.10.2010.

Article data in other languages: croatian

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