Conference paper

Systemic lupus erythematosus and the complement system

Dušanka Martinović Kaliterna ; Department for Clinical Immunology and Rheumatology, Clinic for Internal Medicine, Clinical Hospital Centre Split, Split, Croatia
Jadranka Morović-Vergles ; Department for Clinical Immunology and Rheumatology, Clinic for Internal Medicine, Clinical Hospital “Dubrava”, Zagreb, Croatia
Mislav Radić ; Department for Clinical Immunology and Rheumatology, Clinic for Internal Medicine, Clinical Hospital Centre Split, Split, Croatia

Abstract

The complement system has important protective functions in both, the innate and the adoptive immune systems. Dysregulation of complement system can cause the tissue damage. The complement deficiency predispose to an infection, and also to a development of autoimmune diseases, especially systemic lupus erythematosus (SLE). The complement play an important role in the pathogenesis of SLE, and besides that the lower levels of complement´s compounds are well recognised as marker of SLE activity and also the activity of secondary APS.

Keywords

systemic lupus erythematosus; complement system

Hrčak ID:

125189

URI

https://hrcak.srce.hr/125189

Publication date:

21.11.2009.

Article data in other languages: croatian

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