Editorial

The clinical picture of rheumatoid arthritis - the complex of three independent mechanisms

Hans Georg Fassbender ; Center for Pathology of Rheumatic Diseases of the University Clinics “Johannes Gutenberg”, Mainz, Germany
Carola Meyer-Scholten ; Center for Pathology of Rheumatic Diseases of the University Clinics “Johannes Gutenberg”, Mainz, Germany
Kati Zorn ; Center for Pathology of Rheumatic Diseases of the University Clinics “Johannes Gutenberg”, Mainz, Germany

Abstract

The assumption of inflamation as the only cause of the complex clinical picture of rheumatoid atrhritis does not correspond to facts. We have found and proven the existence of three seemingly unconnected mechanisms, and only their combination can account for the general clinical picture of rheumatoid arthritis. They are: 1. immunologic synovitis, responsible for pain, swelling and stiffnes; 2. oncological process (“tumor-like proliferation”), responsible for the destruction of joints; 3. Primary necrotizing process, responsible for the (sometimes lethal) destructions in the heart and blood vessels.

Keywords

rheumatoid arthritis; synovitis; tumor-like proliferation; primary necrotizing process

Hrčak ID:

125214

URI

https://hrcak.srce.hr/125214

Publication date:

1.7.2009.

Article data in other languages: croatian

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