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Review article

HLA-B27 gene: polymorphism, evolution, distribution, and association with spondyloartopathies

Zorana Grubić ; Department for Tissue Typing, Clinic for Urology, Clinical Hospital Centre Zagreb, Zagreb, Croatia


Full text: croatian pdf 479 Kb

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Abstract

The association between HLA-B27 and ankylosing spondylitis is well established more than thirty years. In spite of numerous studies in this field, a lot of unknown is still present. In this review, polymorphism, evolution, distribution and current pathogenetic hypotheses are presented.

Keywords

HLA-B27; polymorphism; evolution; ankylosing spondylitis; spondyloarthropathies; population study

Hrčak ID:

125881

URI

https://hrcak.srce.hr/125881

Publication date:

1.7.2006.

Article data in other languages: croatian

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