Retinoids in Mammals: A Crystallographic Perspective
; Department of Organic Chemistry, University of Padova and Biopolymer Research Center, C.N.R., Via Marzolo 1, 35131 Padova, Italy
Rodolfo Berni ; Department of Biochemistry and Molecular Biology, University of Parma, Parco Area delle Scienze 231 A, 43100 Parma, Italy
APA 6th Edition
Zanotti, G. & Berni, R. (2002). Retinoids in Mammals: A Crystallographic Perspective. Croatica Chemica Acta, 75 (3), 835-845. Retrieved from https://hrcak.srce.hr/129325
MLA 8th Edition
Zanotti, Giuseppe and Rodolfo Berni. "Retinoids in Mammals: A Crystallographic Perspective." Croatica Chemica Acta, vol. 75, no. 3, 2002, pp. 835-845. https://hrcak.srce.hr/129325. Accessed 6 Oct. 2022.
Chicago 17th Edition
Zanotti, Giuseppe and Rodolfo Berni. "Retinoids in Mammals: A Crystallographic Perspective." Croatica Chemica Acta 75, no. 3 (2002): 835-845. https://hrcak.srce.hr/129325
Zanotti, G., and Berni, R. (2002). 'Retinoids in Mammals: A Crystallographic Perspective', Croatica Chemica Acta, 75(3), pp. 835-845. Available at: https://hrcak.srce.hr/129325 (Accessed 06 October 2022)
Zanotti G, Berni R. Retinoids in Mammals: A Crystallographic Perspective. Croatica Chemica Acta [Internet]. 2002 [cited 2022 October 06];75(3):835-845. Available from: https://hrcak.srce.hr/129325
G. Zanotti and R. Berni, "Retinoids in Mammals: A Crystallographic Perspective", Croatica Chemica Acta, vol.75, no. 3, pp. 835-845, 2002. [Online]. Available: https://hrcak.srce.hr/129325. [Accessed: 06 October 2022]
Retinoids are involved in several essential processes in mammals, including vision, morphogenesis, spermatogenesis and maintenance of epithelial tissue. Since they are labile compounds, nearly insoluble in water, they are present in body fluids and within the cell bound to specific retinoid-binding proteins. In plasma, a single protein, called retinol-binding protein, delivers the alcoholic form of vitamin A from its store sites to target cells. In the cytoplasm, four different cellular retinol-binding proteins and two retinoic acid-binding proteins have been discovered and structurally characterized to date. Finally, two classes of nuclear receptors for retinoic acid isomers have been characterized. The structure/function relationship for several retinoid-binding proteins is discussed here.
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