Original scientific paper

Synthesis and Characterization of Fatty Acid Copper(II) Carboxylates with N,N-Diethylnicotinamide

Bojan Kozlevčar ; Faculty of Chemistry and Chemical Technology, University of Ljubljana, Aškerčeva 5, P. O. Box 537, 1001 Ljubljana, Slovenia
Nina Lah ; Faculty of Chemistry and Chemical Technology, University of Ljubljana, Aškerčeva 5, P. O. Box 537, 1001 Ljubljana, Slovenia
Ivan Leban ; Faculty of Chemistry and Chemical Technology, University of Ljubljana, Aškerčeva 5, P. O. Box 537, 1001 Ljubljana, Slovenia
Franc Pohleven ; Biotechnical Faculty, University of Ljubljana, Rožna dolina, C. VIII/34, 1000 Ljubljana, Slovenia
Primož Šegedin ; Faculty of Chemistry and Chemical Technology, University of Ljubljana, Aškerčeva 5, P. O. Box 537, 1001 Ljubljana, Slovenia

Abstract

A series of new fatty acid copper(II) carboxylates of the composition [(Cu₂(O₂CC_nH_2n+1)₄(Et₂nia)₂)] (Et₂nia = N,N-diethylnicotinamide; n = 6 to 11) were synthesized, characterized and tested for fungicidal activity. The compounds were synthesized and crystallized from aqueous solution only because their solubility in organic solvents is too high. Dimeric structure for ali compounds was proposed (μ_eff at room temperature = 1.43-1.48 BM; UV-Vis λ_max at 350-400 nm; IR, Δν(COO-) = 185-199 cm-1). A binuclear paddlewheel cage structure was found for the compound [(Cu₂(O₂CC₇H₁₅)₄(Et₂nia)₂)] by X-ray diffraction. Screening for fungicidal activity against the woodrotting fungi Trametes versicolor and Antrodia vaillantii shows that the compounds dissolved in DMSO stop mycelium growth completely at a concentration of 1.0 × 10-3 mol L-1. Some of them show strong activity also in more diluted Solutions; however, stronger retardation for Antrodia vaillantii was noticed for all substances.

Keywords

copper(II) carboxylates; fatty acids; diethylnicotinamide; crystal structure; fungicidal activity

Hrčak ID:

132012

URI

https://hrcak.srce.hr/132012

Publication date:

4.9.2000.

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