Original scientific paper

HES solutions in critical illness, trauma and perioperative period

ROBERT BARONICA ; Department of Anaesthesiology, Reanimatology and Intensive Care, University Hospital Centre Zagreb, Kišpatićeva 12, 10 000 Zagreb, Croatia
DANIELA BANDIĆ PAVLOVIĆ ; Department of Anaesthesiology, Reanimatology and Intensive Care, University Hospital Centre Zagreb, Kišpatićeva 12, 10 000 Zagreb, Croatia
ŽELJKO DRVAR ; Department of Anaesthesiology, Reanimatology and Intensive Care, University Hospital Centre Zagreb, Kišpatićeva 12, 10 000 Zagreb, Croatia
SANJA SAKAN ; Department of Anaesthesiology, Reanimatology and Intensive Care, University Hospital Centre Zagreb, Kišpatićeva 12, 10 000 Zagreb, Croatia
DINKO TONKOVIĆ ; University Department of Anaesthesiology, University Hospital Sveti Duh, Zagreb, Croatia
KORALJKA BAČIĆ BARONICA ; University Department of Neurology, University Hospital Sveti Duh, Zagreb, Croatia

Abstract

In the last few years, many studies and meta-analyses have demonstrated that hydroxyethyl starch (HES) solutions increase
the risk of acute renal failure and mortality in critically ill patients. Some studies suggest complete avoidance of HES solutions
in patients of all categories. On the other hand, recent studies and analyses suggest that HES solutions may be used
in hypovolemic critically ill patients and in the perioperative setting. The main problem in everyday clinical practice and in
a rational fluid management approach is that treatment with alternatives to HES solutions is not always pathophysiologically
justified (crystalloids) or confirmed in randomised controlled trials (gelatins, albumins).

Keywords

hydroxyethyl starches; critical illness; perioperative period

Hrčak ID:

134137

URI

https://hrcak.srce.hr/134137

Publication date:

1.6.2014.

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