Professional paper

Neuroleptic malignant syndrome: a case report and discussion

VLATKO GRABOVAC orcid.org/0000-0002-6796-3691 ; Clinical Hospital Dubrava, Gojko Šušak Avenue 6, 10000 Zagreb, Croatia
SEAD ŽIGA ; Clinical Hospital Dubrava, Gojko Šušak Avenue 6, 10000 Zagreb, Croatia
TATJANA KEREŠ ; Clinical Hospital Dubrava, Gojko Šušak Avenue 6, 10000 Zagreb, Croatia
MAŠA SORIĆ ; Clinical Hospital Dubrava, Gojko Šušak Avenue 6, 10000 Zagreb, Croatia

Abstract

Neuroleptic malignant syndrome (NMS) is an emergent, life threatening condition most often seen as an iatrogenic complication
of neuroleptic or antipsychotic treatment. It is characterized by a tetrad of clinical features: mental status changes,
fever, muscle rigidity and autonomic instability, although it is not necessary for all of them to be present at a same time for
working diagnosis to be made. This paper will deal with the case of a 29-year old male patient diagnosed with schizophrenia
who developed NMS, presented as a generalized tonic-clonic seizure and high fever, after 191 days of in-hospital treatment.
After 13 days of hospital treatment in the Intensive Care Unit of Clinical Hospital Dubrava, the patient is in a hemodynamical
and proper quantitative mental state and discharged for further psychiatric treatment at his parent hospital institution.

Keywords

neuroleptic malignant syndrome; neuroleptics; creatine kinase

Hrčak ID:

134170

URI

https://hrcak.srce.hr/134170

Publication date:

1.6.2014.

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