Review article

Molecular detection and genetic characterization of mumps virus

T. Košutić Gulija
M. Šantak
R. Mažuran
M. Baričević
J. Ivančić-Jelečki
R. Jug
D. Forčić

Abstract

Mumps is an RNA virus that is a cause of the vaccine preventable disease, mumps. In clinical specimens and supernatants of the infected cell cultures its RNA is detectable by RT-PCR test. Advantages of RT-PCR are rapidity, specificity and sensitivity. Genetic characterization and genotyping are basis for molecular epidemiological surveillance of the wild type mumps virus. Mumps outbreaks are also detected in a highly vaccinated population. Molecular detection and characterization of wild and vaccine types of mumps virus has been performed in Croatia since the late nineties.

Keywords

Molecular detection; genotyping; molecular epidemiology

Hrčak ID:

12636

URI

https://hrcak.srce.hr/12636

Publication date:

23.3.2007.

Article data in other languages: croatian

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