Original scientific paper

A Simple QSAR Model for Trypsin Aminopeptidase Inhibitory Flavonoids

Dragan Amić ; Faculty of Agriculture, The Josip Juraj Strossmayer University, P. O. Box 117, 31001 Osijek, The Republic of Croatia
Dušanka Davidović-Amić ; Faculty of Agriculture, The Josip Juraj Strossmayer University, P. O. Box 117, 31001 Osijek, The Republic of Croatia
Drago Bešlo ; Faculty of Agriculture, The Josip Juraj Strossmayer University, P. O. Box 117, 31001 Osijek, The Republic of Croatia
Bono Lučić orcid.org/0000-0001-7232-2007 ; The Rugjer Bošković Institute, P. 0. Box 1016, 10001 Zagreb, The Republic of Croatia
Nenad Trinajstić ; The Rugjer Bošković Institute, P. 0. Box 1016, 10001 Zagreb, The Republic of Croatia

Abstract

A simple QSAR model of the trypsin aminopeptidase inhibitory flavonoids has been developed which enables prediction of the inhibitory potency of flavonoids as a function of their molecular properties. Based upon the results obtained, a possible mode of interaction between the flavonoid and its target receptor is proposed.

Keywords

Hrčak ID:

135661

URI

https://hrcak.srce.hr/135661

Publication date:

3.11.1997.

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