Original scientific paper

Ferrocene Compounds. XXI. Synthesis of Some β-Aryl-β-ferrocenylpropionic Acids and β,β-(1 ,1'-Ferrocenylene)bis(β-arylpropionic Acids)

Srđan Lisac ; Faculty of Food Technology and Biotechnology, University of Zagreb, 41000 Zagreb, Croatia
Vladimir Rapić ; Faculty of Food Technology and Biotechnology, University of Zagreb, 41000 Zagreb, Croatia
Spomenka Kovač ; Faculty of Food Technology, University of Osijek, 54000 Osijek, Croatia

Abstract

Reaction of several a-substituted ferrocenylmethanols 1 with diethyl malonate gave condensation products 3, which were hydrolized and decar- boxylated to p-ferrocenylbutyric acid (6a) and p-aryl-p-ferrocenylpropionic acids (6b-6e). Similarly, starting from a,a'-disubstituted l,l'-ferrocenylene- bismethanols 2 p,p-(l,l'-ferrocenylene)bis(butyric acid) (11a) and P,P-(1,1'- ferrocenylene)bis(p-arylpropionic acids) (llb-lle) have been obtained via 8 and 9. The mechanism of these condensation reactions which includes transesterification of diethyl malonate with carbinols 1 and 2 has been proposed.

Keywords

Hrčak ID:

136775

URI

https://hrcak.srce.hr/136775

Publication date:

1.12.1994.

Visits: 606 *