Review article

ORAL ALLERGY SYNDROME

IRENA IVKOVIĆ-JUREKOVIĆ orcid.org/0000-0001-5024-7149 ; Zagreb University Children’s Hospital, Department of Pediatrics, Division of Pulmonology, Allergology, Immunology and Rheumatology, Zagreb, Croatia

Abstract

Oral allergy syndrome (OAS) is an IgE antibody-mediated allergic reaction that occurs after consumption of fresh fruits and vegetables in patients with allergy to pollen. Symptoms arise due to cross-reactivity between pollen and plant-derived food and another term used for this syndrome is pollen-food allergy syndrome. The patient is sensitized with pollen and exhibits an allergic reaction to food antigen with structural similarity to the pollen. OAS is rarely seen in young children, but the prevalence increases with age and OAS is the most common manifestation of food allergy in adolescents and adults. Symptoms are usually localized in the oral mucosa, but abdominal symptoms and anaphylaxis may occur as well. Patients generally tolerate thermally processed food, but in those with atopic dermatitis it may lead to worsening of eczema. In the case of generalized symptoms and anaphylaxis, strict avoidance and first aid measures including a self-injectable adrenaline are advised.

Keywords

allergic rhinitis; food allergy; oral allergy syndrome; pollen-food syndrome

Hrčak ID:

136988

URI

https://hrcak.srce.hr/136988

Publication date:

27.3.2015.

Article data in other languages: croatian

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