Preliminary communication

Synthesis of New Heteropolycyclic Bis-Carboxamide: 3,5-Dichloro-N,N’(p-Chlorophenyl)dithieno [3,2-b:2’,3’-d]Furan-2,6-Carboxamide

Grace M. Karminski-Zamola ; Department of Organic Chemistry, Faculty of Chemical Engineering and Technology, University of Zagreb, 41000 Zagreb, Croatia
Miroslav Malešević ; Department of Organic Chemistry, Faculty of Chemical Engineering and Technology, University of Zagreb, 41000 Zagreb, Croatia
Miroslav Bajić ; Department of Organic Chemistry, Faculty of Chemical Engineering and Technology, University of Zagreb, 41000 Zagreb, Croatia
Gordon Golja ; Department of Organic Chemistry, Faculty of Chemical Engineering and Technology, University of Zagreb, 41000 Zagreb, Croatia

Abstract

New heteropolycyclic bis-carboxamide 5 was synthesized in multistep synthesis starting from furylacrylic acid (1). This type of compounds are now being examined as potential anti-AIDS agent. The most important stage in the multistep synthesis is the preparation of intermediate 3,5-dichloro- dithieno[3,2-b:2’,3’-d]furan-2,G-dicarbonyl chloride (4).

Keywords

Hrčak ID:

137142

URI

https://hrcak.srce.hr/137142

Publication date:

29.1.1993.

Visits: 1.008 *