Original scientific paper

Spin-Spin Relaxation Time Manifestations of Tissue Degradation

Ewald Moser ; Arbeitsgruppe NMR, Institut für Medizinische Physik, Universitat Wien, Wahringerstr. 13, A-1090 Wien, Austria
Gregor Gomišček ; Arbeitsgruppe NMR, Institut für Medizinische Physik, Universitat Wien, Wahringerstr. 13, A-1090 Wien, Austria
Johann Schuster ; Arbeitsgruppe NMR, Institut für Medizinische Physik, Universitat Wien, Wahringerstr. 13, A-1090 Wien, Austria
Peter Holzmüller ; Arbeitsgruppe NMR, Institut für Medizinische Physik, Universitat Wien, Wahringerstr. 13, A-1090 Wien, Austria

Abstract

The changes of spin-spin (Tz) relaxation time in rat liver and muscle biopsies after tissue excision were investigated by low resolution NMR spectrometry.
Relaxation times Tz were determined during the first four hours after the tissue excision at 9-minute time intervals, keeping the tissue at constant temperature. Series of measurements were performed at three different temperatures (7, 20, 37 °C). Changes in pH were measured under the same experimental conditions.
Due to degradation processes after tissue excision, molecular and structural changes take place in the cells and are manifested in variations of Tz value.
An empirical relation is suggested to describe the observed correlation between
Tz and pH, as well as temperature in the excised liver and muscle tissue.

Keywords

Hrčak ID:

137293

URI

https://hrcak.srce.hr/137293

Publication date:

15.6.1992.

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