Review article

Clinical nutrition and colorectal cancer

Željko Krznarić orcid.org/0000-0003-3758-4540
Ana Kunović

Abstract

Cachexia-anorexia syndrome, characterized by anorexia and loss of adipose tissue and skeletal muscle mass, is common feature in majority of patients with cancer, especially in cancer localized in gastrointestinal tract. Malnutrition is recognized as a negative prognostic factor in patients with colorectal cancer. Malnutrition in cancer patients reduces response to specific oncological therapy, slows down recovery after surgical treatment, leads to impairement of quality of life and decreases survival. It is considered that developement of cancer cachexia is a multifactorial process, however inflammation plays a major role. Therefore, targeting inflammation may represent an effective strategy to prevent/treat cachexia. Treatment should be patient-tailored and based on a multimodal approach.

Keywords

colorectal cancer; cancer anorexia-cachexia syndrome; nutritional support; eisosapentanoeic acid; megestrol ‒ acetate

Hrčak ID:

139033

URI

https://hrcak.srce.hr/139033

Publication date:

14.5.2015.

Article data in other languages: croatian

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