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Medicina Fluminensis : Medicina Fluminensis, Vol. 51 No. 3, 2015.

Review article

Pathophysiology of cancer pain

Jelena Vukelić orcid id orcid.org/0000-0001-5828-9087 ; Klinika za otorinolaringologiju i kirurgiju glave i vrata, KBC Rijeka, Rijeka
Renata Dobrila-Dintinjana ; Klinika za radioterapiju i onkologiju, KBC Rijeka, Rijeka
Stjepko Pleština ; Klinika za onkologiju, KBC Zagreb, Zagreb

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Abstract

Pain is an unpleasant sensory and emotional experience associated with actual or potential tissue damage or described in terms of such damages. Cancer pain is divided into: nociceptive, neuropathic and inflammatory. Nociceptive pain occurs by irritation of nociceptors that are peripheral pain receptors. Neuropathic pain is caused by damage to the peripheral or central nervous system, without simultaneous stimulation of nociceptors. Pain is a subjective feeling, and consequently two person can experience different stimuli of equal intensity. Different perception of pain is explained by the different activation of analgesic system which monitors conduction of pain impulses in the central nervous system. The objective of this paper is to present the pathophysiological mechanism of pain in cancer patients.

Keywords

analgesia; cancer; pain

Hrčak ID:

144061

URI

https://hrcak.srce.hr/144061

Publication date:

1.9.2015.

Article data in other languages: croatian

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