Professional paper

Combination therapy with perindopril / amlodipine - optimal synergy in the treatment of arterial hypertension and cardiovascular risk reduction

Josipa Josipović ; University Hospital Centre Sestre milosrdnice, Zagreb, Croatia
Dajana Katičić ; University Hospital Centre Sestre milosrdnice, Zagreb, Croatia
Draško Pavlović ; University Hospital Centre Sestre milosrdnice, Zagreb, Croatia

Abstract

Arterial hypertension is the leading modifiable cardiovascular risk factor. In 75% of patients, the combination antihypertensive therapy is required to achieve target values of blood pressure (BP). The combination therapy leads to greater lowering of BP and faster achievement of target values whereas the fixed combination simplifies the treatment and improves the patient compliance. The combination of ACE inhibitors and calcium channel blockers, in addition to an additive effect on lowering the value of BP, provides an additional benefit in reducing the overall cardiovascular risk.

Keywords

ACE inhibitors; calcium channel blockers; hypertension; perindopril; amlodipine

Hrčak ID:

146870

URI

https://hrcak.srce.hr/146870

Publication date:

21.5.2014.

Article data in other languages: croatian

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