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Acta Dermatovenerologica Croatica, Vol. 23 No. 3, 2015.

Other

Crude Coal Tar and Ultraviolet (UV) A radiation (Modified Goeckerman Technique) in Treatment of Psoriasis

Mohamed A. El-Darouti ; Dermatology Department, Faculty of Medicine, Cairo University
Heba I. Gawdat ; Dermatology Department, Faculty of Medicine, Cairo University
Rehab A. Hegazy ; Dermatology Department, Faculty of Medicine, Cairo University
Amira M. Tawdy ; Dermatology Department, Faculty of Medicine, Cairo University
Marwa M. Fawzy ; Dermatology Department, Faculty of Medicine, Cairo University
Dalia M. Abdel Halim ; Dermatology Department, Faculty of Medicine, Cairo University

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Abstract

Background: Psoriasis is a chronic inflammatory dermatosis that has a substantial impact on the quality of life. Goeckerman's technique (GT) has been recruited for the treatment of psoriasis with high clearance rates and long periods of remission.

Psoriasis is a chronic inflammatory dermatosis that has a substantial impact on the quality of life. Goeckerman’s technique (GT) has been implemented for the treatment of psoriasis with high clearance rates and long periods of remission. The objective of this article was to evaluate the efficacy and safety of modified GT (crude coal tar 2.5% plus UVA) as an alternative therapeutic modality for psoriatic patients with skin types III-V. Twenty two patients with moderate, severe, and erythrodermic psoriasis were included in this study. All patients received modified GT (crude coal tar 2.5% plus UVA) six days per week for a period of 3 months. Assessment of the rate of reduction of psoriasis area severity index (PASI) was performed, as well as photographic documentation of each patient at baseline and after completion of therapy. There was a significant reduction in PASI scores after therapy in all patients (P=0.001). The rate of PASI reduction after therapy was >50% in 63.6% of patients; 27.3% of patients achieved >75% reduction and 9.1% of patients achieved 26-50% reduction. No serious side effects were reported in any of the patients. Modified GT is a safe and effective therapeutic option for patients with moderate and severe psoriasis.

Keywords

Psoriasis; Modified GT; Efficacy; Safety

Hrčak ID:

147139

URI

https://hrcak.srce.hr/147139

Publication date:

16.10.2015.

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