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Progression of Conjunctival Primary Acquired Melanosis (PAM) to Widely Spreaded Malignant Melanoma

Sonja Jandroković orcid.org/0000-0003-0536-1502 ; Department of Ophthalmology, University Hospital Center Zagreb, Zagreb, Croatia
Smiljka Popović-Suić ; Department of Ophthalmology, University Hospital Center Zagreb, Zagreb, Croatia
Jelena Juri Mandić ; Department of Ophthalmology, University Hospital Center Zagreb, Zagreb, Croatia
Tomislav Kuzman ; Department of Ophthalmology, University Hospital Center Zagreb, Zagreb, Croatia
Ivan Škegro ; Department of Ophthalmology, University Hospital Center Zagreb, Zagreb, Croatia
Marija Barišić Kutija ; Department of Ophthalmology, University Hospital Center Zagreb, Zagreb, Croatia
Sanja Masnec ; Department of Ophthalmology, University Hospital Center Zagreb, Zagreb, Croatia
Miro Kalauz ; Department of Ophthalmology, University Hospital Center Zagreb, Zagreb, Croatia

Abstract

Primary acquired melanosis (PAM) is an acquired pigmentation of the conjunctival epithelium, a preinvasive pigmented
lesion. When it is associated with cellular atypia it can lead to the developement of melanoma. We report a case
report of malignant melanoma of the conjuntiva, which arrised from the conjuntival PAM. The disease was too extensive
for ocular conservation, therefore exenteration was performed. This case highlights the need for regular follow-up of patients
with melanocytic lesions of the ocular adnexa, and particular attention to the surgical technique, and careful followup
to detect further disease activity.

Keywords

conjuntival malignant melanoma; primary acquired melanosis; local extension; orbital exenteration

Hrčak ID:

147432

URI

https://hrcak.srce.hr/147432

Publication date:

26.12.2014.

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