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COMPARATIVE EFFECTS OF HONEY BASED AND SILVER/CHARCOAL BASED DRESSINGS ON THE HEALING OFVENOUS LEG ULCERS
TANJA PLANINŠEK RUČIGAJ
; University Medical Centre Ljubljana, Department of Dermatovenereology, Ljubljana, Slovenia
MAJA MIHELIČ
; University of Ljubljana, Medical Faculty, Ljubljana, Slovenia
Abstract
Infections, bioilms and critical colonization are frequently observed in venous ulcers. Silver and charcoal are used to control bacterial colonization, whereas honey dressings are useful for cleaning and healing owing to their antioxidant and antibacterial properties. Matrix metalloproteinases are often found in excess in chronic wounds, which can be regulated with polyhydrated ionogens. This clinical study included 60 patients whose ulcers stopped healing, were at risk of infection, with foul odor or discoloration of granulation tissue. one group was treated with honey based dressing (hBD, MelMax™) and the other group with silver/charcoal based dressing (S/CD, Actisorb silver™). Plotting the measured wound areas in both groups during the trial revealed signiicant differences in the effects of both dressings. In hBD group, ulcer size was reduced by a mean of 36.7% in 44 days on average. In contrast, in S/CD group, ulcer size stagnated with a mean 2.8% decrease in 42 days on average. These data clearly show that honey based dressings are best for chronic wounds that are critically colonized, infected or lined with different bioilms. They beneit from faster cleaning and healing; in addition, these patients need less additional systemic antibiotics.
Keywords
honey based dressing; silver/charcoal cased dressing; venous leg ulcers
Hrčak ID:
148113
URI
Publication date:
8.11.2015.
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