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PATOPHYSIOLOGY OF WOUND HEALING
TOMISLAV NOVINŠČAK
; Department of Emergency Medicine, Međimurje County, Čakovec, Croatia
MARINKO FILIPOVIĆ
; Čakovec General Hospital, Department of Surgery, Čakovec, Croatia
Abstract
Wound healing is a basic, highly complex, logical and well orchestrated physiologic process of interaction of various speciic molecules and cells in normal tissue function and structure restoration. In essence, genetically deined and by reined physical and chemical forces driven process, in most living beings wound healing leads to imperfect but suficient tissue repair. Some rare exceptions in wound healing, like salamander or human fetus, that can achieve complete and perfect regeneration provide us with some new horizons. The knowledge of the normal healing phases, as well as insight into the pathophysiology mechanisms, have upgraded one of the four basic contemporary medicine principles (ars medica, the art of healing). This article emphasizes the importance of normal wound healing attainment and numerous factors that impair healing processes, thus resulting in chronic wounds or delayed wound healing. Apparently, a broader insight into the wound healing processes allows various clinicians a slightly more sovereign and eficient chronic wound care.
Keywords
wound healing; pathophysiology; chronic wound; delayed healing
Hrčak ID:
148116
URI
Publication date:
8.11.2015.
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