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Review article

THE LONG ROAD TO THE USE OF MICROSCOPE IN CLINICAL MEDICINE IN VIVO: FROM EARLY PIONEERING PROPOSALS TO THE MODERN PERSPECTIVES OF OPTICAL BIOPSY

Giovanni Ponti ; Surgical, Medical and Dental Department of Morphological Sciences related to Transplant, Oncology and Regenerative Medicine, University of Modena and Reggio Emilia, Modena, Italy
Umberto Muscatello ; Department of Physics, University of Modena and Reggio Emilia, Modena, Italy


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Abstract

For a long period the scientists did not recognized the potentialities of the compound microscope in medicine. Only few scientists recognized the potentialities of the microscope for the medicine; among them G. Campani who proposed the utilization of his microscope to investigate the skin lesions directly on the patient. The proposal was illustrated in a letter Acta Eruditorum of 1686. The recent development of optical techniques, capable of providing in-focus images of an object from different planes with high spatial resolution, significantly increased the diagnostic potential of the microscope directly on the patient.

Keywords

clinical use of microscope; Campani’s mocroscope; optical biopsy in vivo

Hrčak ID:

152059

URI

https://hrcak.srce.hr/152059

Publication date:

15.12.2015.

Article data in other languages: croatian

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