Original scientific paper
Circulating histamine levels and lung function test in cotton mill workers
H. Yenkatakrishna-Bhatt
; National Institute of Occupational Health, Meghani Nagar, Ahmedabad (Gujarat), India
N. Mohana-Rao
; National Institute of Occupational Health, Meghani Nagar, Ahmedabad (Gujarat), India
G.M. Panchal
; National Institute of Occupational Health, Meghani Nagar, Ahmedabad (Gujarat), India
P.K. Kulkarni
; National Institute of Occupational Health, Meghani Nagar, Ahmedabad (Gujarat), India
Abstract
Circulating histamine level and forced expiratory volume in one second (FEY1) were measured by conventional methods in 39 selected workers (24 exposed and 15 controls) employed in a local cotton mill. There were 12 workers with byssinosis, who complained of breathlessness and tightness in the chest, showed elevated histamine concentrations in blood and a diminished percentage of predicted FEY1 values. Non-byssinotic subjects who were exposed to cotton dust had lower blood histamine concentrations and a higher percentage of predicted FEY1 values. Both exposed groups exhibited enhanced histamine levels and a lower percentage of predicted FEV1 values than unexposed subjects. The circulating histamine concentrations were negatively correlated with FEV1 among exposed workers.
Keywords
Hrčak ID:
152472
URI
Publication date:
15.6.1989.
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