Case report

Invasive Cell Grading - An Overview

Mirko Ivkić
Vladimir Bedeković
Livije Kalogjera
Hrvoje Čupić
Željko Ferenčić

Abstract

Pathohistologic diagnosis plays a pivotal role in therapeutic modalities for cancer, and acts as a prognostic factor. The histologic grade is a numeric expression of tumor differentiation and is linked to patient outcome. Broders' scoring system is still widely used in scoring squamous cell carcinomas. New data suggest that in the most invasive parts of a malignant tumor, the morphology and biologic behavior differ from the central and superficial areas of the same tumor. A new invasive cell grading system has been proposed as a better prognostic factor in the multifactorial diagnostic and therapeutic approach to the patient with malignant tumor. Numerous studies performed to date have provided sufficient evidence to propose the invasive cell grading system to be introduced instead of the "old" Broders' scoring system.

Keywords

Carcinoma - diagnosis; Carcinoma - pathology; Carcinoma - prognosis

Hrčak ID:

14740

URI

https://hrcak.srce.hr/14740

Publication date:

2.9.2002.

Article data in other languages: croatian

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