Original scientific paper

Mould growth and aflatoxin accumulation in the presence of newly synthetized analogues of dehydroacetic acid

K. Tkalčević ; Laboratory of Microbiology and Laboratory of Organic Chemistry, Faculty of Food Science and Biotechnology, Zagreb, Croatia
S. Duraković ; Laboratory of Microbiology and Laboratory of Organic Chemistry, Faculty of Food Science and Biotechnology, Zagreb, Croatia
I. Sušnik Rybarski ; Laboratory of Microbiology and Laboratory of Organic Chemistry, Faculty of Food Science and Biotechnology, Zagreb, Croatia
Z. Duraković ; Department of Internal Medicine, University Hospital Rebro, Zagreb, Croatia
O. Pospišl ; Laboratory of Microbiology and Laboratory of Organic Chemistry, Faculty of Food Science and Biotechnology, Zagreb, Croatia
B. Radić ; Institute for Medical Research and Occupational Health
Lj. Bračević ; Ruder Boskovic Institute, Zagreb, Croatia

Abstract

Dehydroacetic acid (DHA) and its newly synthetized analogues, 4-hydroxy-3(p-toluoyl)-6-(p-tolil)-2H-pyrane-2-one (DHT) and 5-bromo-4-hydroxy-3-(p-toluoyl)-6-(p-tolil)-2H-pyrane-2-one (BrDHT), were tested for antifungal and antiaflatoxigenic acitivity in experiments with the aflatoxigenic mould Aspergillus parasiticus NRRL 2999. DHT and DHA concentrations of 3.0 µ.M and 6.0 µ.M respectively stimulated mould growth and aflatoxin B, and G, synthesis, but concentrations higher than 30.0 µ.M produced an inhibitory effect. In the presence of low BrDHT concentrations mould growth decreased by 70% and toxin concentrations by 85% and 90%, respectively.

Keywords

Hrčak ID:

153019

URI

https://hrcak.srce.hr/153019

Publication date:

22.6.1988.

Article data in other languages: croatian

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