Paediatria Croatica, Vol. 59 No. 3, 2015.
Original scientific paper
https://doi.org/10.13112/PC.2015.23
Oral manifestations in human immunodeficiency virus infected pediatric patients receiving and not receiving antiretroviral therapy: a cross sectional study
Abstract
The aim of the study was to assess and compare oral manifestations of human immunodefi ciency virus (HIV) infected pediatric
patients undergoing antiretroviral therapy (ART) and those not undergoing ART. A cross sectional study included HIV positive children
(receiving and not receiving ART) aged 5-15 years, registered at the District Hospital ART Centre, Udaipur, and HIV negative
schoolchildren. HIV related oral lesions were diagnosed according to the World Health Organization criteria. Sociodemographic and
other related information were also recorded. CD4+ cell count was determined in all study subjects. The χ2
-test, stepwise multiple
linear regression and logistic regression were used on statistical analysis. In all tests, confi dence interval and p-value were set at 95%
and ≤0.05, respectively. A greater proportion of HIV patients receiving treatment had CD4+ cell count of more than 750 cells/mm3
.
The majority of HIV patients receiving ART for more than three years and only 20% of those not receiving ART were free from any oral
lesions. The results of the present study demonstrated ART to be eff ective in reducing the prevalence of HIV related oral lesions, as
already described in the literature; however, unlike previous studies, the present paper reports more valid fi ndings for having included
most of the confounding variables
Keywords
Antiretroviral therapy, highly active; HIV; oral manifestations
Hrčak ID:
153103
URI
Publication date:
25.9.2015.
Visits: 1.327 *