Review article

PATIENT WITH PEPTIC ULCER DISEASE

NIVES RADOŠEVIĆ QUADRANTI ; Primorsko-goranska County, Health Centre, Krešimirova 52a, Rijeka, Croatia
INES DIMINIĆ-LISICA ; University of Rijeka Medical Faculty and Dr. Ines Diminić-Lisica Family Medicine Office, Rijeka, Croatia
NINA BAŠIĆ MARKOVIĆ ; Family Medicine Practice Nina Bašić Marković, Rijeka, Croatia
BRANISLAVA POPOVIĆ ; University of Rijeka Medical Faculty and Family Medicine Practice Branislava Popović, MD, Rijeka, Croatia

Abstract

Peptic ulcer disease is represented by a lesion in the mucosa of the digestive tract due to imbalance of its aggressive and protective
mechanisms. The main external factors of the development of peptic ulcers are Helicobacter pylori infection and the use of non-steroidal anti infl ammatory drugs (NSAIDs) and acetylsalicylic acid (ASA). Symptoms of peptic ulcer disease are a common reason for visiting the family physician. All patients with symptoms of dyspepsia under the age of 50 and without the alarm symptoms should be tested whether H. pylori is present by performing the Urea Breath Test or stool antigene testing, and infection, if found, should be treated. Endoscopic examination is obligatory in patients older than 50 years and those with alarm symptoms. „Sequential therapy“ is recommended in Croatia as the fi rst-line treatment of H. pylori infection, or triple therapy that comprises applying a proton pump inhibitor (PPI) in combination with amoxicillin and metronidazole. Four weeks after eradication therapythe control testing for H. pylori should be performed.

Keywords

peptic ulcer; Helicobacter pylori; eradication therapy; dyspepsia

Hrčak ID:

154155

URI

https://hrcak.srce.hr/154155

Publication date:

12.3.2016.

Article data in other languages: croatian

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