Review article
ETIOLOGY OF PROSTATE CANCER
JOSIP GALIĆ
; Josip Juraj Strossmayer University, School of Medicine, Osijek, Croatia
ŽELJKO VIDAS
; Josip Juraj Strossmayer University, School of Medicine, Osijek, Croatia
IVAN SAVIĆ
; Dubrava University Hospital, Zagreb, Croatia
DAMIR ŠTAJCAR
; Polyclinic Sveti Nikola, Varaždin, Croatia
ZORAN RAJKOVIĆ
; Zabok General Hospital, Zabok, Croatia
NUHI ARSLANI
; Maribor University Hospital, Maribor, Slovenia
LUKA VUČEMILO
; Merkur University Hospital, Zagreb, Croatia
JOSIP BUBNJAR
; Zabok General Hospital, Zabok, Croatia
DINO PAPEŠ
; Zagreb University Hospital Center, Zagreb, Croatia
Abstract
Prostate cancer is now recognized as one of the most important medical problems in male population. Epigenetic regulation of gene expression by promoter methylation and histone acetylation, proinfl ammatory enzyme cyclooxygenase-2 and somatic mutations in a variety of genes with diverse biological functions has been implicated in prostate cancer
development and progression.
Keywords
prostate gland; cancer; etiology; epigenesis
Hrčak ID:
154197
URI
Publication date:
13.3.2016.
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