Short communication, Note

Cobalt and manganese interaction in the liver of rat

S.V.S. Rana ; School of Environmental Contamination and Toxicology, Department of Zoology, D. A. V. (P. G.) College, Muzaffarnagar, lndia
R. Prakash ; School of Environmental Contamination and Toxicology, Department of Zoology, D. A. V. (P. G.) College, Muzaffarnagar, lndia
V.P. Agrawal ; School of Environmental Contamination and Toxicology, Department of Zoology, D. A. V. (P. G.) College, Muzaffarnagar, lndia

Abstract

The effects of cobalt and manganese on some enzymes in the rat's liver were studied. Manganese invariably inhibited the activity of alkaline phosphatase, acid phosphatase, glucose-6-phosphatase, cholinesterase and lipase, whereas cobalt affected only the activities of acid phosphatase, glucose-6-phosphatase and lipase. After a combined treatment with both cobalt and manganese (a mixture containing one half of LD50 each) only the activity of acid phosphatase decreased, while the activities of other enzymes remained within the normal range, indicating an antagonistic behaviour of these essential trace elements.

Keywords

Hrčak ID:

155134

URI

https://hrcak.srce.hr/155134

Publication date:

10.10.1986.

Article data in other languages: croatian

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