Short communication, Note
EFFECTS OF PLATELET-RICH PLASMA IN THE TREATMENT OF CHRONIC ULCER
ZRINJKA PAŠTAR
orcid.org/0000-0002-8478-8784
; Ministry of Defence Republic of Croatia and Department of Health Studies, University of Zadar, Zadar, Croatia
SANDRA MARINOVIĆ KULIŠIĆ
; Zagreb Clinical Hospital Center, Clinical Department of Dermatovenereology, Zagreb, Croatia
Abstract
A venous ulcer is area of discontinuity of the skin, usually localised in distal parts of the lower legs. The aetiology is associated with chronic venous disease-venous hypertension. The size and shape of venous ulcer can be different and it may even cover all circumferential of extremity. Additionally, along with basic therapy possibilities, there are many different dressings. Therefore the knowledge of each characteristic of dressing on process of epithelisation is essential as well as treating the biofilm that is responsible for complications and persistence of ulcer. One of additional therapy possibility is platelet-rich plasma. Platelet-rich plasma is a developing area for clinicians and researchers for bioregeneration in multiple fields of medicine including dermatology. Autologous platelet-rich plasma with its growth factors and proteins accelerates bioregeneration. However, better understanding of the mechanisms and development of standardized protocols with well-designed studies are needed.
Keywords
platelet-rich plasma; ulcers; dermatologic indications
Hrčak ID:
155194
URI
Publication date:
5.4.2016.
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