Original scientific paper
Relationship between pulmonary diffusing capacity and indices of airway obstruction in patients with chronic obstructive bronchitis
I. Mandura
; Institut za kliničku fiziologiju, Medicinski fakultet, Priština, Kosovo
M. Jakupi
; Institut za kliničku fiziologiju, Medicinski fakultet, Priština, Kosovo
M. Haxhiu
; Institut za kliničku fiziologiju, Medicinski fakultet, Priština, Kosovo
Abstract
The relationship between pulmonary diffusing capacity, specific airway resistance (SRt = Rt x ITGV), and spirographic measurements was studied in 472 patients with chronic bronchitis. The results showed that pulmonary diffusing capacity was reduced in a group of patients with chronic bronchitis associated with moderate or severe airway obstruction. In this group the best correlation was noted between pulmonary diffusing capacity and vital capacity. However, a wide variability of data was present, which can be explained by means of a wide range of physiological values in healthy persons, and by inhomogeneity of alveolar ventilation. Furthermore, it was found that the degree of reduction of diffusing capacity in cases of chronic obstructive bronchitis can be predicted on the basis of VC, FEV1, and capillary P02 and PC02 data. Despite a very wide variability of pulmonary diffusing capacity, its impairment in patients with chronic bronchitis suggests the development of pulžmonary emphysema.
Keywords
Hrčak ID:
156789
URI
Publication date:
23.1.1986.
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