Short communication, Note

Metabolizam anorganskog olova u profesionalno eksponiranih ljudi

S. Skerfving ; Department of Occupational Medicine, Lund University, Lund, Sweden and Departments of Radiation Physics, Malmo General Hospital, Malmo, and University of Gothenburg, Gothenburg, Sweden
L. Ahlgren ; Department of Occupational Medicine, Lund University, Lund, Sweden and Departments of Radiation Physics, Malmo General Hospital, Malmo, and University of Gothenburg, Gothenburg, Sweden
J.-O. Christoffersson ; Department of Occupational Medicine, Lund University, Lund, Sweden and Departments of Radiation Physics, Malmo General Hospital, Malmo, and University of Gothenburg, Gothenburg, Sweden
B. Haeger-Aronsen ; Department of Occupational Medicine, Lund University, Lund, Sweden and Departments of Radiation Physics, Malmo General Hospital, Malmo, and University of Gothenburg, Gothenburg, Sweden
S. Mattsson ; Department of Occupational Medicine, Lund University, Lund, Sweden and Departments of Radiation Physics, Malmo General Hospital, Malmo, and University of Gothenburg, Gothenburg, Sweden
A. Schütz ; Department of Occupational Medicine, Lund University, Lund, Sweden and Departments of Radiation Physics, Malmo General Hospital, Malmo, and University of Gothenburg, Gothenburg, Sweden

Abstract

Napravljena je matematička analiza smanjenja razine olova u 29 radnika pomoću modela s dva kompartmenta. Spori dio kompartmenta imao je vrijeme polovičnog nestanka od otprilike pet godina, a brzi od otprilike jedan mjesec. Postojale su značajne individualne varijacije. Razina olova u falangama kretala se između 20 i 135 mg/kg, kao što je utvrđeno fluorescentnom metodom s X-zrakama u 73 aktivna i umirovljena radnika. Razina olova u kosti rasla je s vremenom ekspozicije s maksimumom od 10 mg/kg. U umirovljenih radnika postojala je povezanost između koncentracije olova u kosti i one u krvi. Povećanje od 100 do 150 mg/kg u kosti odgovaralo je otprilike 1.5 µmol/L. Koncentracija olova u spinalnim nastavcima kralješaka bila je često veća ili manja od one u falangama, što upućuje na postojanje barem dvaju kompartmenta. Razina olova u kosti može poslužiti u praktične svrhe za procjenu moguće interne ekspozicije olovu mobiliziranjem iz skeleta.

Keywords

Hrčak ID:

157866

URI

https://hrcak.srce.hr/157866

Publication date:

3.10.1984.

Article data in other languages: english

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