Original scientific paper
Theoretical possibilities of predicting some harmful effects of different chemicals on mammals by using a physical expression
V. Veljković
; Institut "Boris Kidrič", Beograd, Srbija
V. Vojvodić
; Vojnomedicinska akademija JNA, Beograd, Srbija
Abstract
The correlation between the mean potential of the electron-ion interaction and the pesticidal, bactericidal and fungicidal properties of some chemicals was investigated. The chemical structure of the compounds was a basas for predicting possible harmful effects on mammals. In order to prove the usefulness of these calculations the authors compared own results with the data on chemical carcinogenesis in experimental animals of the International Agency for Research on Cancer in Lyon. The method can also be used for predicting beneficial effects of some new chemicals and identifying compounds with a greater biological activity. The preliminary results obtained with this method are valuable and can serve for planning more extensive research of chemical hazards in experimental animals.
Keywords
Hrčak ID:
158839
URI
Publication date:
5.4.1982.
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