Original scientific paper
THE POSSIBILITIES OF COLPOSCOPY IN RECOGNITION OF THE LATENT CERVICAL HPV INFECTION
Nikola Tuškan
Vesna Kljajo
Miroslav Furdek
Emil Tuškan
Abstract
Objective. The concept of latent HPV infection implies the presence of viral genome within morphologically normal cells. Therefore the latent HPV infection couldn’t be diagnosed by either cytologic or histologic examinations but by DNA hibridization. Our intention was to examine the possibilities of colposcopy in recognition of the latent cervical HPV infection. Methods. There were two groups of examinees selected for testing with DNA hibridization. In the first there were 65 women recently treated with combined therapy because of subclinic HPV infection. The cytologic and colposcopic examinations were performed 3 months after therapy completed. In the second group there are 52 examinees with cytologic signs of CIN without koilocytosis. Hibridization tests and colposcopy were performed in all examinees. Results. Hibridization tests were positive in 38 patients (58,46%) of the first group and in 34 (65,38%) of those of the second group. Colposcopic findings in both groups of examinees with positive hibridization tests showed microcapillary contours, irregular widths of the intercapillar spaces with poor fine-caliber vessels in 70,83% of them. Conclusions. A common colposcopic signs in patients with latent HPV infection of the uterine cervix are the findings of the microcapillary contours, irregular widths of the intercapillar spaces and fine-caliber vessels, poorly formed patterns. Colposcopy could be used for presumptive recognition of latent HPV infection of the uterine cervix.
Keywords
uterine cervix; latent HPV infection; colposcopy
Hrčak ID:
15541
URI
Publication date:
1.12.2003.
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