Psychiatria Danubina, Vol. 26 No. 3, 2014.
Original scientific paper
LIFETIME HYPOMANIC SYMPTOMS IN REMITTED PATIENTS WITH SCHIZOPHRENIA AND OTHER PSYCHOTIC DISORDERS
Kürsat Altınbas
; Department of Psychiatry, Faculty of Medicine, Çanakkale Onsekiz Mart University, Çanakkale, Turkey
Sema Yesilyurt
; Department of Psychiatry, Bagcilar Research and Training Hospital, Istanbul, Turkey
Hatice Aras
; Department of Psychiatry, Akyazi State Hospital, Sakarya, Turkey
Daniel J. Smith
; Department of Psychiatry, Institute of Health and Wellbeing, University of Glasgow, Glasgow, United Kingdom
Nick Craddock
; Department of Psychological Medicine, Cardiff University School of Medicine, Cardiff, United Kingdom
Abstract
Background: Clinical, genetic and neuroimaging studies indicated strong evidence against traditional diagnostic separation of
bipolar disorder from schizophrenia. In this study, we aimed to evaluate hypomanic symptoms and influence on general functioning
among psychotic patients.
Subjects and methods: Patients with schizophrenia and other psychotic disorders were assessed between June and September
2010. Positive and Negative Symptom Scale (PANSS), Hypomania Check List-32 (HCL-32), Mood Disorders Questionnaire (MDQ)
and General Assessment of Functioning Scale (GAS) were applied to all 93 patients. Answers of self-rating scales were confirmed
with hospital records.
Results: Mean age was 35.7±9.5 years, mean age of onset was 20.3±5.3 years and duration of illness was 15.4±9.2 years. 30.1%
of the patients, had a history of mood stabilizer treatment taken at least one month while one five of the patients had different
psychiatric diagnosis other than current diagnosis. 26.9% of the patients with psychotic disorders had positive scores on both MDQ
and HCL-32 but there were no significant difference between patients in terms of general functioning (p=0.82).
Conclusions: As reported in this study, there is no simple, clear-cut between schizophrenia and bipolar affective disorder.
Keywords
schizophrenia - hypomanic symptoms – dimensions - classification
Hrčak ID:
162135
URI
Publication date:
18.9.2014.
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