Psychiatria Danubina, Vol. 26 No. 4, 2014.
Review article
IS NON-PHARMACOLOGICAL TREATMENT AN OPTION FOR CERTAIN SCHIZOPHRENIA PATIENTS?
Valentin P. Matei
; ''Prof Al Obregia'' Psychiatric Hospital, UMF Carol Davila Bucharest, Bucharest, Romania
Alexandra I. Mihailescu
; ''Prof Al Obregia'' Psychiatric Hospital, UMF Carol Davila Bucharest, Bucharest, Romania
Michael Davidson
; Department of Psychiatry, Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel
Abstract
Background: Schizophrenia treatment has been debated at length and presently pharmacological treatment is being advocated
as the most beneficial for patients. However, research has shown contradictory results regarding the suitability of pharmacological
treatment for certain groups of schizophrenia patients.
Methods: The present review discusses results from the literature indicating good outcomes only for patients who adhered to
prescribed pharmacological treatments. It also describes studies favoring non-drug treatments in certain schizophrenic patients.
Results: The authors described two groups of patients where the long-term use of neuroleptics may be useless, if not harmful.
The first group comprised schizophrenic people with a single psychotic episode and therefore very good prognosis. In their case, the
prolonged use of antipsychotics would not be beneficial due to pharmacological and social (stigma) side effects. Further research is
warranted to identify and investigate biological, environmental, and psychological factors associated with single-episode
schizophrenia. The second group comprised ultra-resistant schizophrenic patients. In their case, in the absence of a therapeutic
response in acute episodes or aggressive behavior, clinicians should use short episodes of treatment with benzodiazepines or other
sedative medications such as mood stabilizers.
Conclusions: The present paper attempted to answer the important question as to whether all schizophrenic people should be
treated with antipsychotics for the same good prognosis. The authors have provided solutions for better outcomes in a greater
number of patients using alternative treatment after identifying schizophrenic patients who should not receive neuroleptic treatment.
Suggestions for future research are also discussed.
Keywords
schizophrenia – neuroleptics - non-pharmacological treatment
Hrčak ID:
162212
URI
Publication date:
15.12.2014.
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