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https://doi.org/10.20471/acc.2016.55.02.21

Refractory bradycardia – a rare complication of carboprost tromethamine for induction of abortion

Jasna Čerkez Habek ; Department of Cardiology, Clinical Department of Internal Diseases, Sveti Duh University Hospital, Zagreb, Croatia
Dubravko Habek ; Clinical Department of Obstetrics and Gynecology, Sveti Duh University Hospital, Zagreb, Croatia; Croatian Catholic University, Zagreb, Croatia
Dario Gulin ; Department of Cardiology, Clinical Department of Internal Diseases, Sveti Duh University Hospital, Zagreb, Croatia

Abstract

We report a first case of refractory several-hour sinus bradycardia, a rare but already described side effect of intramuscular administration of carboprost tromethamine to induce abortion for medical indication in a patient without cardiovascular and other diseases. After administration of
atropine sulfate 3x0.5 mg intravenously without effect, the patient‘s sinus rhythm spontaneously normalized as carboprost was eliminated from the body (it has a 3-hour half-life). It is reasonable to believe that the specific prostaglandin underlay the etiology of bradycardia.

Keywords

Prostaglandins; Carboprost tromethamine; Bradycardia; Case reports

Hrčak ID:

164884

URI

https://hrcak.srce.hr/164884

Publication date:

1.6.2016.

Article data in other languages: croatian

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